News
Urban Night Lights Linked to Increased Stroke Risk, Study Finds
The research calls attention to the necessity of urgent steps aimed at prevention of negative health effects of night lights of the cities and polluting air on the risk of strokes.
United States – The brilliant skyline of the metropolis might look appealing at first, but according to the latest research, it may increase a person’s stroke rate.
Urban Lights Linked to Increased Stroke Risk
A recent study has revealed that dark night lights cause a physiological phenomenon: They damage blood circulation, making strokes possible, as reported by The HealthDay.
The largest risk factor for diseases that lead to blood vessel infection of the brain is exposure to outdoor light at night, which is the result.
These include the rupture or blockage of arteries that transport the blood to the brain and blood leaking into the brain, the two main causes of stroke.
From this marked difference, we can say that “we advise people, especially those living in urban areas, to consider reducing that exposure to protect themselves from its potentially harmful impact,” Dr. Jian-Bing Wang from the Zhejiang University School of Medicine in Hangzhou, China, said in a news release.
Artificial light is overused nearly everywhere in the world; four out of five people live in places where the light is not bright, as it says in background notes.
Study Methodology and Results
In the study, Wang and colleagues used satellite data on more than 28,300 adult persons residing in China and measured their levels of exposure to outdoor nighttime light with light pollution maps obtained from the Nighttime Lights Satellite (NLS).
This middle-aged couple lived in Ningbo, a metropolis with close to 8 million people on the southeastern coast of China.
In six years of follow-up from 2015 to 2021, the researchers reported around 1,300 cases of cerebrovascular disease and 777 ischemic strokes, where arteries were clogged, and 133 hemorrhagic strokes, where the brain bled.
Call for Action on Environmental Factors
It was found that repeated exposure to light during the night results in melatonin suppression, a neurotransmitter that contributes to sleep.
However, the lights could be the reason stroke risk is increasing due to the fact that they disturb good sleep, according a group of researchers.
“We need to develop more effective policies and prevention planning to reduce the burden of disease from environmental factors such as light as well as air pollution, particularly for people living in the most densely populated, polluted areas around the world,” Wang said.
In addition, researchers ascertained that a person was more prone to a stroke if air pollution was present.
Those who are exposed to the highest amount of particular air pollution (fuel combustion, dust, or smoke) have a 41% to 50% higher chance of stroke than the least exposed group, as reported by The HealthDay.
The researchers concluded that the nitrogen oxide emissions from the vehicles and industrial power lines increase the risk of getting stroke by 31% in the people who lived in the most contaminated areas.
News
Hunter Biden’s Ex-Wife to Testify in Firearm Possession Case
The trial will involve whether Hunter Biden falsely stated about his drug use in a bid to buy a pistol: witness accounts from his former wife and former girlfriends.
United States – Hunter Biden’s ex-wife is set to testify about what the young Biden’s drug habits were as a defense claim in a case that suggests he lied about them to possess a firearm.
On charges of possession of a firearm by a user of a controlled substance, prosecutors said they would prove that Hunter Biden allowed his anti-drug screening test to come back clean when he purchased a revolver in October 2018, knowing that he was a drug user, as reported by Reuters.
The jurors viewed the text messages, banking records, and some clips of the audiobook of the Then Hunter Biden memoir that the prosecutors say show the client was habitually using crack at the time he bought the gun, one day after the purchase.
“Addiction is not a crime. Lying is,” prosecutor Derek Hines said.
Hunter Biden, 54 years old, has not quit guilty to three felonies, charging him with filing false information while purchasing the gun and possession of the prohibited firearm for 11 days.
The trial comes in the wake of another precedent setting case; the criminal indictment of former President of the United States, Donald Trump, who became the first US president to be convicted of a felony last week. Trump is the Republican candidate for president against Joe Biden of the Democratic party in the Nov. 5 poll.
Something was not mentioned at Hunter Biden’s trial regarding that aspect, but the prosecution used the phrase “no one is above the law.
Testimonies and Defense
Hines said that jurors would hear Kathleen Buhle, Hunter Biden’s ex-wife, and his former girlfriend, Zoe Kestan, and Hallie Biden, who was his brother, Beau Biden’s wife. They all can testify about Hunter Biden’s problems with drugs and alcohol throughout the years, Hines noted.
Prosecution’s Evidence and Statements
Lowell, who has represented Hunter Biden in an ongoing grand jury investigation, noted that his client contradicted these claims in his memoir titled “Beautiful Things,” published in 2021. Hunter Biden’s lawyer insisted that the evidence would demonstrate the subject was sober when purchasing the firearm and viewed himself as ‘not a user’ at the time.
Context and Political Backdrop
Trump is expected to be sentenced on July 11th after he was convicted by a jury in the state court in New York last Thursday of 34 felonies of presenting fake documents to conceal payments made to a pornographic actor ahead of a sex scandal that might have had an impact on the build-up to the 2016 U. S. election, as reported by Reuters.
He has denied the allegations in three other ongoing criminal charges, two against him for his attempts to overturn his 2020 defeat by Biden and one for keeping top-secret materials at his Florida estate after his presidency in 2021.
News
FDA Debate Looms Over MDMA Therapy’s Role in PTSD Treatment
The FDA on MDMA therapy for PTSD is going to usher a new era in the therapeutic management of mental health with implications in treatment for millions of patients with the disorder.
United States – An important meeting on the approval of a new treatment using one of the substances considered hallucinogens is to be held on Tuesday as the advisers to the US Food and Drug Administration are set to deliberate on the therapy based on MDMA for PTSD.
The session, conducted by the independent experts of the agency, is the closest that a drug based on MDMA, commonly referred to as ecstasy or molly, has ever gotten within the FDA procedure for approval, as reported by Reuters.
Addressing Mental Health Needs
This comes after several similar efforts have been pursued by supporters claiming that substances such as MDMA are effective in the treatment of mental health and millions also have other uses that are not related to drug use in society.
The treatment is a capsule containing or containing pure MDMA manufactured by the public-benefit corporation Lykos Therapeutics and to be taken in combination with hourly, full-spectrum sessions of talk therapy by a licensed, entheogenic mental health provider.
Promising Results and Concerns
MDMA, in combination with consultation, has indicated lower PTSD scores in trials with over 190 patients in contrast to placebo.
However, the FDA’s staff reviewers voiced concerns on Friday about how patients suffering from PTSD in the clinical trials knew whether they were given MDMA or a placebo due to the mind-altering effects of the drug.
A Step Towards Innovation
“I don’t think that is as much of a concern because even if it is an enhanced placebo effect, people are still getting better,” said David Olson, director of the UC Davis Institute for Psychedelics and Neurotherapeutics.
“But the bigger question is, what is the risk to those individuals?”
PTSD is among the largely prevalent mental health disorders, which impacts 13 million people within the United States of America and is prevalent among war veterans. This indicates that there is still a big gap in the development of new treatments for PTSD in this regard since the other drugs do not affect every person.
Lykos treatment is one treatment out of many psychedelic drugs given to patients with untreatable mental disorders, including Compass Pathways’ (CMPS. O) drug, which is derived from magic mushrooms.
The agency’s staff discussed restrictions on its use and oversight in briefing documents delivered on Friday. The FDA also pointed out the increase in both blood pressure and pulse in the trials and instances of hepatic toxicity.
According to Olson, the approval could provide “a new way to attack the problem, but as a single agent, it is not going to be a large driver” because of the cost and logistical challenges associated with it, as reported by Reuters.
“It’s important because it would be the first in this class of molecules, but I don’t think it will be the last; it will be replaced by compounds that have superior properties to MDMA.”
News
British Tech Pioneer Faces Fraud Charges in HP Acquisition Trial
The fraud trial of Lynch is a follow-up on the disastrous HP-Autonomy interface, which has been a significant turning point on the technology as well as corporate governance.
United States – Jurors at the trial of British tech pioneer Mike Lynch may hear closing arguments in San Francisco on Monday in the fraud case regarding Hewlett-Packard’s (HPE. N) acquisition of Lynch’s software company Autonomy for USD 11.2 billion in 2011.
The Cambridge University-educated businessman testified for the defense at the trial, explaining that he had no criminal intentions and that HP performed the merger poorly, as reported by Reuters.
HP then proceeded to write down the value of Autonomy by USD 8.8 billion in one year since the acquisition.
Lynch and the former Autonomy finance executive Stephen Chamberlain have been charged with fraud and conspiracy for planning to artificially increase the company’s revenue starting in 2009, in part to attract a buyer.
Allegations of Fraud
Prosecutors claimed the two inflated Autonomy revenue through back-dated transactions and ‘round-trip’ transactions, where money was paid upfront by the customer through a fictitious contract.
During the trial, which started mid-March, the jurors were presented with over thirty government witnesses, including Leo Apotheker, the former HP chief who was dismissed just a few weeks after the purchase of Autonomy was declared.
Lynch’s legal advisors prepared the trial, stating that HP wanted to acquire Autonomy ahead of potential competitors, so the due diligence was performed quickly before the sale was closed.
Lynch Denies Involvement in Accounting Decisions
Taking the stand, Lynch denied that he was involved directly with the accounting decisions at issue and asserted that he was more concerned with technology issues at the time, leaving the finance-related matters in the hands of Sushovan Hussain, Autonomy’s former chief financial officer.
Hussain was convicted in 2018 in the same court in another trial. He was released from U. S. prison in January following his five-year imprisonment term.
Lynch was identified as one of the UK’s leading tech enablers in a bracket that included Steve Jobs of Apple and Bill Gates of Microsoft.
Fallout from Controversial Acquisition Continues
The Autonomy deal was one of the largest British technology deals that was supposed to boost HP’s software segment. Rather, it gave rise to a chain of cruel and costly court proceedings, as reported by Reuters.
Lynch and Hussain were found liable for the defamation in a civil trial in London in 2022, though the amount of the damages remains unconcluded. The company is requesting 4 billion US Dollars in total funding.